Single-cell genomics to comprehensively understand healthy B-cell maturation and transformation to chronic lymphocytic leukemia

SPOTlight: seeded NMF regression to deconvolute spatial transcriptomics spots with single-cell transcriptomes (opens in new window)

Author(s): Marc Elosua-Bayes, Paula Nieto, Elisabetta Mereu, Ivo Gut, Holger Heyn
Published in: Nucleic Acids Research, Issue 49/9, 2021, Page(s) e50-e50, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkab043

Sampling time-dependent artifacts in single-cell genomics studies (opens in new window)

Author(s): Ramon Massoni-Badosa, Giovanni Iacono, Catia Moutinho, Marta Kulis, Núria Palau, Domenica Marchese, Javier Rodríguez-Ubreva, Esteban Ballestar, Gustavo Rodriguez-Esteban, Sara Marsal, Marta Aymerich, Dolors Colomer, Elias Campo, Antonio Julià, José Ignacio Martín-Subero, Holger Heyn
Published in: Genome Biology, Issue 21/1, 2020, ISSN 1474-760X
Publisher: BMC, Nature Publishing Group
DOI: 10.1186/s13059-020-02032-0

The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome (opens in new window)

Author(s): Martí Duran-Ferrer, Guillem Clot, Ferran Nadeu, Renée Beekman, Tycho Baumann, Jessica Nordlund, Yanara Marincevic-Zuniga, Gudmar Lönnerholm, Alfredo Rivas-Delgado, Silvia Martín, Raquel Ordoñez, Giancarlo Castellano, Marta Kulis, Ana C. Queirós, Seung-Tae Lee, Joseph Wiemels, Romina Royo, Montserrat Puiggrós, Junyan Lu, Eva Giné, Sílvia Beà, Pedro Jares, Xabier Agirre, Felipe Prosper, Ca
Published in: Nature Cancer, Issue 1/11, 2020, Page(s) 1066-1081, ISSN 2662-1347
Publisher: Nature Publishing Group
DOI: 10.1038/s43018-020-00131-2

IGLV3-21R110 identifies an aggressive biological subtype of chronic lymphocytic leukemia with intermediate epigenetics (opens in new window)

Author(s): Ferran Nadeu, Romina Royo, Guillem Clot, Martí Duran-Ferrer, Alba Navarro, Silvia Martín, Junyan Lu, Thorsten Zenz, Tycho Baumann, Pedro Jares, Xose S. Puente, José I. Martín-Subero, Julio Delgado, Elías Campo
Published in: Blood, Issue 137/21, 2021, Page(s) 2935-2946, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1182/blood.2020008311

A single-cell tumor immune atlas for precision oncology (opens in new window)

Author(s): Paula Nieto, Marc Elosua-Bayes, Juan L. Trincado, Domenica Marchese, Ramon Massoni-Badosa, Maria Salvany, Ana Henriques, Juan Nieto, Sergio Aguilar-Fernández, Elisabetta Mereu, Catia Moutinho, Sara Ruiz, Patricia Lorden, Vanessa T. Chin, Dominik Kaczorowski, Chia-Ling Chan, Richard Gallagher, Angela Chou, Ester Planas-Rigol, Carlota Rubio-Perez, Ivo Gut, Josep M. Piulats, Joan Seoane, Joseph E. P
Published in: Genome Research, Issue 31/10, 2021, Page(s) 1913-1926, ISSN 1088-9051
Publisher: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gr.273300.120